What is Pramipexole
Pramipexole is a dopamine agonist: originally designed for treating Parkinson’s, now it’s way more popular among athletes due to its effect on prolactin levels.
Increased prolactin levels can cause many unwanted side effects, specifically gynecomastia, even if the estrogen levels are in line. Prolactin-induced gynecomastia can be linked to the Deca-Durabolin or Trenbolone solo cycles. The side effects are dose- and cycle-dependent, yet it’s better to be cautious and add Pramipexole to the cycle.
Pramipexole Benefits
Athletes who have added Pramipexol to their cycles reported the following positive effects of the drug:
Managing Prolactin Levels
If a person considers starting on a Deca-only cycle, it’s recommended to include Pramipexole.
Improving Mood
Some anabolic steroids can cause mood swings, aggression, and other negative side effects. Pramipexole will help to avoid them.
Increased Motivation
As a dopamine agonist, Pramipexole helps athletes follow their training regimen and stay motivated.
Enhanced Sexual Performance
If the athlete has any sexual issues due to Deca-Durabolin usage, starting on Pramipexole will mitigate them and increase the libido.
Pramipexole Side Effects
The drug can cause such side effects as:
- Nausea;
- Headaches and dizziness;
- Insomnia;
- Compulsive behavior (ex., sexual);
- Loss of appetite.
In some cases, they may include hallucinations, tremors, muscle spasms, polyuria, or constipation. However, users do not report those side effects as often.
Pramipexole Contraindications
It’s not recommended to take Pramipexole if the person has any of the following conditions:
- Hypotension;
- NMS;
- Psychosis;
- OCD;
- Renal dysfunction.
If the person took a dosage that exceeded the recommended one, there may be a need to seek medical care.
Pramipexole Dosage
Athletes can take 0.5–1 mg twice a week or take the drug every day. If Pramipexole is to be administered daily, it’s recommended to start with a lower dosage of 0.1 mg and increase it after a few days up to 0.3 mg.
How to Take Pramipexole
When to take |
No significant difference in timing, but should be taken EOD |
Dosage |
0.5–1 mg per week or up to 0.3 mg per day |
Cycle Length |
Equal to the steroid cycle length |
Food Interaction |
Haven’t been reported, can be administered with or without food |
Alcohol Interaction |
Limit alcohol consumption |
Drugs Interaction |
Pramipexole can’t be taken with Benadryl, Xanax, Zyrtec, Risperidone, or Clozapine. |
If the dose has been missed, you shouldn’t double down. However, it’s important to point out that if the dose has been exceeded or missed, there might be a need to start titrating all over.
How to Store Pramipexole
Pramipexole should be stored in a dry, dark place. Do not use Pramipexole if it hasn’t been properly stored or has expired.
Common Questions About Pramipexole
Do You Gain Weight on Pramipexole?
There is some evidence that suggests that Pramipexole can increase your weight. However, this side effect is rare and can be managed with a proper diet and training regimen.
Does Pramipexole Increase Libido?
Yes, Pramipexole can significantly increase libido and improve your sexual function. Moreover, some users have reported compulsive sexual behavior.
Does Pramipexole Lower Blood Pressure?
Pramipexole can lower blood pressure. That’s why this drug isn’t suitable for individuals with hypotension.
Brand: Pharmacy Grade, Apotex, Cobalt, Sandoz, TEVA
Substance: Pramipexole
Dosage and packing: 1 mg/tab (10 tabs)