Cytomel - T3

Cytomel Description

Cytomel (liothyronine sodium) is a synthetically manufactured prescription thyroid hormone. It specially consists of the L-isomer of the natural thyroid hormone triiodothyronine (T3). Thyroid hormones stimulate basal metabolic rate and are involved with many cellular functions including protein, fat, and carbohydrate metabolism. Liothyronine sodium is used medically to treat hypothyroidism, a condition where the thyroid gland does not produce sufficient levels of thyroid hormone. Hypothyroidism is usually diagnosed with a serum hormone profile (T3, T4, & TSH), and may manifest itself with symptoms including loss of energy, lethargy, weight gain, hair loss, and changes in skin texture. T3 is the most active thyroid hormone in the body, and consequently, liothyronine sodium is considered to be a more potent thyroid medication than levothyroxine sodium (T4).

Bodybuilders and athletes are attracted to Cytomel for its ability to increase metabolism and support the breakdown of body fat. Most often utilized during contest preparation or periods of cutting, the drug is usually said to significantly aid in the loss of fat, often on higher levels of caloric intake than would normally be permissive of such fat loss. To this end, the drug is also commonly used in conjunction with other fat loss agents such as human growth hormone or beta-agonists. Some users also ascribe the ability of thyroid hormones like liothyronine sodium to increase the anabolic effect of steroids. While in theory, these drugs may support the greater utilization of protein and carbohydrates for muscle growth, they are not widely proven or accepted for this purpose.

History

The first medication that included T3 was technically a thyroid extract, first given to a patient with myxedema (a skin disorder associated with hypothyroidism) in 1891.¹ Natural thyroid extracts contained therapeutically viable levels of the thyroid hormones T3 and T4 and were widely used in medical practice for more than 60 years. In the 1950s, however, these drugs slowly start giving way to new synthetic thyroid medications, namely liothyronine sodium and levothyroxine sodium, which were consistent in dosage and effect, and more desirable to consumers than prepared animal extracts. Although liothyronine sodium and levothyroxine sodium are both widely available in the U.S. and abroad to this day, liothyronine retains a significantly smaller portion of the global thyroid market. Given its more potent and fast-acting effect, however, liothyronine sodium remains a popular thyroid drug with bodybuilders and athletes. Cytomel® is the most recognized trade name for the drug in the U.S, where it is presently sold under the King Pharmaceuticals brand name.

Cytomel Benefits

• Bodybuilding athletes especially adore Cytomel since for women; low metabolism is hereditary; it is difficult for them to achieve today's levels necessary for competitive norms. A terrible dietary restriction, counting calories up to one-thousandth a day, can be avoided by taking Cytomel. Women are more susceptible to various side effects, but they tolerate the drug well at a 50 mcg dosage per day. Short-term use of the drug in a reasonable dosage is less harmful to health than a low-calorie diet.

• As already mentioned, Cytomel is a hormonal medication. The active ingredient in it is sodium liothyronine, which is similar in properties to L-triiodothyronine, produced by the thyroid gland. To be more precise, Cytomel is a synthetic analog of a natural hormone, so there is no need to fear personal intolerance to the drug.

• Taking this drug improves metabolism since the drug is an analog of a natural hormone. Its action aims to normalize metabolism, and additional consumption of the drug in combination with the hormone in the body accelerates it. As a result, the amount of fatty tissue decreases due to accelerated metabolism because the body, having processed food, begins to process its reserves.

• Athletes who take Cytomel in low doses report the best effect on the body of simultaneously taken steroids, which is explained by the speedy protein metabolism. Until recently, athletes, especially bodybuilding athletes, took the drug for long months to be elastic and stay in shape for a whole year.

How Supplied

Cytomel is most commonly supplied in oral tablets of 5 mcg, 25 mcg, and 50 mcg.

Structural Characteristics

Liothyronine sodium is a synthetic form of T3 thyroid hormone. It has the chemical designation l-tyrosine,o-(4- hydroxy-3-iodophenyl)-3,5-diiodo-,monosodium salt.

Warnings

FDA requires the following black box warning to accompany prescription liothyronine sodium products sold in the U.S.: Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.

Side Effects

Cytomel is practically harmless if taken according to all recommendations. However, overdose can cause:

• irregular heartbeats

• spikes in blood pressure

• sleep problems

• internal anxiety

• panic attacks

• diarrhea

• excessive weight loss

But this is all in extreme cases, and mostly the side effect of excessive hormone consumption is limited to:

• nausea

• headache

• hand tremors

Administration

When used to treat mild hypothyroidism, the typical recommended starting dosage of Cytomel is 25 mcg daily. The daily dosage then may be increased by no more than 25 mcg every 1 to 2 weeks. The established maintenance dose is usually 25-75 mcg per day. Once a day administration of the full daily dose is usually recommended. Although liothyronine sodium is fast-acting, its effects may persist in the body for several days after discontinuance.

The usual protocol among bodybuilders and athletes taking Cytomel to accelerate fat loss involves initiating its use with a dosage of 25 mcg per day. This dosage may be increased by 25 mcg every 4 to 7 days, usually reaching a maximum of no more than 75 mcg per day. As in a medical setting, the intent of this slow buildup is to help the body become adjust to the increasing thyroid hormone levels and avoid sudden changes that may initiate side effects.

Cycles of Cytomel usually last no longer than 6 weeks, and the administration of the drug should not be halted abruptly. Instead, it is discontinued in the same slow manner in which it was initiated. This usually entails reducing the dosage by 25 mcg every 4 to 7 days. This tapering is done so that the body has time to readjust its endogenous hormone production at the conclusion of therapy and to avoid the onset of side effects.

Availability

Liothyronine is an old and widely prescribed medication. It can be found readily in most areas of the world and is sold in a variety of different brand and generic forms. Counterfeiting is not a large-scale problem. It is important to note that one should never purchase an injectable form of this drug. These are generally used as emergency room products only, with potentially very dangerous side effects if misused.

References

1. The emergence of endocrinology. Welbourn RB. Gesnerus. 1992;49 Pt 2:137-50.

Tiromel is a drug used in bodybuilding when the production of essential hormones L-thyroxine and triiodothyronine - are disrupted. This negatively affects the functioning of various body systems. This active hormone T3, which provides the body with energy, regulates metabolism, growth functions, blood flow, and development. Lack of these hormones slows down these processes.

It is mostly used for hypothyroidism (a disease where the thyroid gland does not produce enough thyroid hormone, a deficiency of thyroid hormones in the body). This disease slows down the body's metabolic processes; thus, the accompanying symptoms are weight gain, excessive fatigue, hair loss, and increased sensitivity to the cold. The main problem in patients with hypothyroidism is a blurred perception of what is happening. This is a severe disease that affects most metabolic processes in our body.

Also used to treat:

1. Metabolic disorders
2. Fatigue
3. Thyroid cancer
4. Myxedema
5. Cretinism
6. Hypothyroid obesity
7. Endemic and Sporadic goiter

In the presence of various pathologies of the thyroid gland, L-thyroxine and triiodothyronine (important hormones) are disturbed.

The production of such hormones as L-thyroxine and triiodothyronine are distributed in the presence of various pathologies of the thyroid gland; thus, this negatively affects the functions of multiple body systems, including the cardiovascular, digestive, and nervous. The drug Tіromel allows us to compensate for the deficiency of triiodothyronine (T3 hormone).

The active ingredient of the drug is liothyronine, which is a synthetic thyroid hormone (T3). A person cannot live without thyroid hormones, but their lack is common. In a normal functioning in the body, the thyroid gland produces the prehormone thyroxine, which in the kidneys, skin, liver, and brain is converted into the T3 hormone - liothyronine. This T3 hormone, which:

• provides the body with energy
• regulates metabolism, growth functions, blood flow, and development in general. Lack of T3 hormones slows down these processes. This drug is available as a generic medication, was approved for medical use in 1956. Cytomel and Liothyronine are analogs of the drug.

Patients who have myocarditis, untreated adrenal insufficiency, or cachexia should take this medication with caution. Its use is prohibited if you have:

• tachycardia
• tachyarrhythmia
• heart failure
• diabetes mellitus
• or if you are an older person.

Besides, it would be best if you were careful about people who have hypersensitivity to the active substances of the drug or thyrotoxicosis; in this case, it is recommended to reconsider the treatment. It is not recommended to use it during pregnancy as part of combination therapy to treat the hyperfunction of the thyroid gland in combination with thyreostatic agents, since this can lead to hypothyroidism in the fetus.

Patients who have used Tiromel note that the tablets replenish the missing thyroid hormone, relieve swelling, and also increase the body's endurance. It is often used to treat obesity, but you should be cautious about the doses, as there is a risk of causing some side effects.

Now the best and easiest way to buy a drug is in a pharmacy. However, if you want to order the medication online, you will not have big problems. In modern times, many sites are ready to help with this. You can buy Tiromel online on our website without a prescription.

Tiromel Benefits

1. One of these drug's primary functions is to increase the level of T4 hormone due to natural T3. It increases tissue oxygen demand, stimulates tissue growth and definition, and increases basal metabolism (proteins, fats, and carbohydrates). In small doses, it has an anabolic effect, and in large amounts, it has a catabolic effect.
2. It can be combined with other medicines. For example, Clenbuterol for even more fat burning if you are preparing for a competition. In 1999, a study was conducted, where 33 Lithuanian patients with hypothyroidism noticed that combination therapy "may improve mood and neuropsychological function."
3. Tiromel is very popular among bodybuilders, amateur, and professional athletes(especially during the competition). In this way, they make their metabolism work better and control the amount of fat. Some athletes have been using the drug for years or even decades. Just imagine, your metabolism will be the same as teenagers'.
4. In fitness, the drug is used for weight loss. Based on the fact that a high level of Tiromel's amount accelerates metabolism, thereby encouraging the body to burn more fat and calories. Thus, you can not limit yourself in calorie intake and save your nerves, counting calorie intake.
5. A great advantage is the fact that Tiromel rarely disappoints its consumers. This substance takes first place on the preferred drug list when it comes to sportspeople and professional athletes. In particular, if you want to reach your peak performance, then this is the choice for you. ("Levothyroxine has indeed been used for decades and the overwhelming majority of patients are satisfied," - says Douglas S. Ross, MD, professor of medicine at Harvard Medical School and co-director of Thyroid Associates at Massachusetts General Hospital in Boston).
6. To buy this drug, you need to visit a pharmacy or place an order online, as you like. To order Tiromel online is as easy as to get it. An even more significant plus of buying a drug online is that you can see « Tiromel t3 for sale» and make a purchase in a moment.

Administration and Dosage

Tіromel is a potent hormone that is usually not used for long-term use. The drug dose during the cycle can be adjusted both up and down, while the standard range is 10-100 mcg per day. At the end of the treatment cycle, the dose is reduced gradually, abrupt discontinuation of the drug is not recommended. The standard dosage is 25 mg, and the maximum dosage is 100 mg. Available in pill form. One tablet contains 25 mcg of liothyronine; as a rule, it is in this daily volume that the medicine is prescribed for adults. It is forbidden to use the hormone on your own, without examination and specialist advice. In case of overdose, you can get thyrotoxicosis and hypothyroidism.

In most cases, in treating hypothyroidism, it should be taken once a day (dosage 25 mcg). Take orally 30 minutes before meals. Changes will be visible after about two weeks from the start of treatment. After the results, you can make further conclusions. If there is no progress, a higher dosage is prescribed. Of course, different cases require different treatments.

With myxedema, the initial dose is five mcg per day. Every 1-2 weeks, increase by 5-10 mcg. When a 25 mcg dose is reached, a further increase is carried out by 5-25 per day every 1-2 weeks. The maintenance dose is 50-100 mcg/day.

With a non-toxic goiter, the initial dose of five mcg per day is increased by 5-10 mcg every 1-2 weeks. The maintenance dose - 75 mcg/day.

Suppressive test with T3: with increased absorption of 131I by the thyroid gland, it is prescribed in a dose of 75-100 mcg/day for seven days, then the test is repeated.

In children and the elderly, the initial dose is five mcg/day, and then it is gradually increased by five mcg/day.

The drug is not suitable for long-term therapy. When prescribing the treatment of a drug with indirect anticoagulants and oral hypoglycemic drugs, it is necessary to control the blood coagulation time and the level of glycemia.

Tirol's cycles last 3-4 weeks. After that, you should reduce consumption or combine it with some other drugs, such as Clenbuterol.

Tiromel T3 Cycle

Week Dose

Then it is recommended to take a break for 2-3 weeks and repeat the course.

Tiromel Side Effects

Side effects include:

• headache
• irritability
• tachycardia
• arrhythmia
• angina pectoris
• a progression of heart failure
• dysmenorrhea
• allergic reactions.

The most dangerous effect is an overdose.

In case of an overdose, arrhythmia, increased sweating, anxiety, irritability, weight loss, increased appetite, diarrhea, tremors, fever, vomiting, headache are possible. It is best to induce vomiting or try activated charcoal. Otherwise, resort to symptomatic treatment.

It should be noted that рhenytoin, salicylates, dicumarol, antidepressants, cardiac glycosides, ketamine increase the concentration and risk of side effects.

Before buying Tiromel, be sure to consult your doctor for a competent Tiromel prescription. Self-medication is dangerous for your health!