About Agmatine
Agmatine 100mg/mL, offered by Innovagen, is a premium injectable supplement. As an NMDA antagonist, this compound — (4-aminobutyl)guanidine in aqueous solution — has a whole range of benefits for bodybuilders.
Agmatine sulfate is a great overall support compound with a wide range of effects, from better pumps to stress relief.
How Does It Works
Agmatine’s mechanism of action relies on several pathways, including acting as an NMDA receptor antagonist, enhancing nitric oxide synthesis, and modulating ion channel functions.
In more details, we can focus on 3 main aspects:
- As an NMDA receptor antagonist, it modulates glutamate (an excitatory neurotransmitter) and reduces neuronal excitability;
- Agmatine upregulates nitric oxide (NO) production and activates endothelial nitric oxide synthase. It also enhances vasodilation (makes your capillaries expand a bit and improves blood flow to muscle tissue);
- In terms of hormonal release — Agmatine influences the release of pituitary hormones and reduces cortisol (the stress hormone) levels through hypothalamic action.
As a result of these actions, you get quite a long list of benefits.
Agmatine Benefits
Not all are equally beneficial for bodybuilding directly, but it’s an overall support compound and health is just as important as your gains:
- Cardiovascular health — reduced arterial stiffness with enhanced nitric oxide bioavailability, get a healthier heart and less blood pressure issues;
- Pain management — analgesic properties of Agmatine come from blocking NMDA receptors and other ion channels involved in pain signaling. Less pain, more energy;
- Neuroprotection — the compound has a potential to protect your brain from oxidative stress;
- Muscle mass and workouts — better blood flow with Agmatine means enhanced muscle pump and improved insulin sensitivity. Work out longer, with more effectiveness;
- Mental health — finally, through modulation of neurotransmitters, Agmatine may help alleviate symptoms of depression and anxiety. Just what you need with Trenbolone’s mental side effects.
How to Take Agmatine
For the best results from Agmatine by Innovagen, follow this protocol:
- Dosage — Stick to 100 mg per injection;
- Method — Administer through intramuscular injection (glutes, deltoids, quads);
- Timing — works best if you inject it pre-workout, in about 30 minutes.
When to take?
Agmatine is best taken around 30 minutes before exercise to maximize its effects on blood flow and nutrient delivery.
How long does it take to work?
You’ll notice the effects within 15-30 minutes after the administration, depending on the dosage and individual metabolism.
Best Stacks
Agmatine can be stacked with other compounds with no interactions. For example:
- Anabolic steroids — to reduce neurotoxicity, reduce mental side effects, improve blood flow;
- SARMs or Peptides — for the same reasons, to enhance some of the effects of the SARM/peptide cycle;
- With Panacea by Innovagen — for more mental effects (enhanced anti-stress and relaxation, just not before the workout).
Innovagen Agmatine FAQ
Is Agmatine sulfate safe?
Agmatine sulfate is considered safe for most. Unless you have an allergy or get an unusually bad response to the substance, if used within the recommended dosage guidelines, Agmatine is safe.
Is Agmatine addictive?
Agmatine is not addictive; it does not produce psychological or physical dependency. You’ve heard about AGmatine and addiction because it’s now widely researched as the opposite: a way to combat nicotine addiction, alcohol and benzos addictions.
Is Agmatine sulfate a stimulant?
No, agmatine sulfate does not act as a stimulant and does not produce stimulatory effects typical of substances like caffeine. It’s an NMDA antagonist: working in the same area as stimulants, with neurotransmitters, though not causing the same effects.
Is Agmatine the same as arginine?
It’s a derivative of Arginine. Agmatine is derived from arginine through a process called decarboxylation but functions differently within the body. Also, Agmatine sulfate is naturally produced in the human body as a byproduct of arginine metabolism.
It’s like saying that a wooden chair is the same as a tree: both are kinda made from wood and have similar properties, material-wise, but they’re not the same.
How does Agmatine make you feel?
It’s highly individual, but most athletes report increased mental clarity and a moderate mood lift. Also, you’ll get a great pumping effect in the gym, along with reduced pain and enhanced performance.
Dosage and packing: 100mg/mL, 10mL