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Everything You Should Know Before Going on a Steroid Cycle After 40

Everything You Should Know Before Going on a Steroid Cycle After 40

If you think you can’t go on a steroid cycle after 40 ― you’re wrong. Here are the 3 best steroid protocols for men over 40 years old in 2025 by Muscle Gear.

You can start working out at any age if you take proper precautions. The same goes for anabolic steroids; it’s not just for men in their 20s. In fact, steroid usage is pretty common among older men (40+ years).

The recent study has found that men in their 40s turn to steroids more often, and not only self-appointed TRT or HGH. We’re talking Deca, Primo, and Test. The compound choice is heavily linked to specific purposes: muscle-building, anti-aging, weight loss, or just enhancing overall well-being. 

But first, let’s discuss what’s going on with your body once you get closer to 40-50 years, so you could understand your needs better and choose the right cycle.

Andropause: what is it and how does it affect you

Andropause is a natural condition associated with low testosterone levels. As men age, their total and free test levels decline. When your total testosterone has reached a mark lower than 15 nmol/L, you can experience the following symptoms:

  • Low libido and erectile dysfunction;
  • Fatigue, dizziness, excessive tiredness;
  • Brain fog and low focus;
  • Sleep disturbances, irritation, and depression;
  • Weight gain, muscle weakness, and soreness;
  • Hot flashes.

When you’re in your early twenties, your testosterone levels are generally high (if you don’t have any medical conditions); from there, it starts to go downhill, no exceptions.

Andropause can strike when you are 30, 35, 40, or 50, it will depend on your genetics, lifestyle, nutrition, and stress levels. One thing that’s perfectly clear ― it sucks. But there’s a way to restore your testosterone levels and feel better.

How can andropause be reversed

TRT (Testosterone Replacement Therapy) 250mg/mL 10mL - Apoxar
Apoxar TRT (Testosterone Decanoate) is a longer-acting ester of Testosterone, optimal for hormone replacement therapy (HRT). Usage: 500-1000 mg weekly, adjust if needed. Cycle Duration: From 8 weeks, TRT duration is not
$85.00
5

TRT can help you return to your normal routine and feel more energized and confident. You can even increase your muscle mass and reduce your body fat content without going for high Test dosages. It doesn’t get more natural than this, so side effects are pretty much nonexistent:

  • Typical TRT dosage: 100-200 mg/week;
  • PED dosage: 300-600 mg/week, 10-12 weeks.

It’s important to do the blood work before taking steroids to make sure that you won’t put your health at risk. 

Since cardiovascular issues can be a problem during a Test cycle, it’s recommended to undergo a thorough check-up: ECG, CT, stress tests, lipid profile. You’ll also want to monitor your blood pressure, especially if you’re prone to BP spikes.

Testosterone and HGH Cycle After 40

Somatropin 100IU Growth Hormone HGH - Apoxar
Growth Hormone — recommended for muscle building, fat loss, anti-aging, and injury healing. Usage: 2-3 IU for healing/anti-aging, 4-6 IU for muscle growth Cycle Duration: a minimum of 6 months Quality Guaranteed: Lab Test
$425.00
5

Growth hormone levels decline with age, just like Testosterone. Adding HGH to your TRT can be beneficial for muscle growth, body composition, endurance, and sexual function. It’s a popular compound for anti-aging therapy.

However, it’s contraindicated for those who have cancer, severe cardiovascular conditions, or diabetes. If there are no such issues ― go for it.

Goal

HGH Dosage

Weight Loss

2-4 IU/day

Joint Support

2-3 IU/day

Anti-Aging Effects

1-3 IU/day

Muscle Growth

3-6 IU/day

If you haven’t used HGH before, start with 1-2 IU/day and gradually increase the dosage. Even though it’s a natural hormone, it can cause unwanted side effects if misused or incorrectly introduced to the body.

Best bulking cycles for men after 40 in 2025

If your diet and daily routine are in order, and you’ve trained for at least 2-4 years, you can look into anabolic steroid cycles. However, there are some limitations due to the age and heightened risks of renal or hepatic failure and cardiovascular events:

  • You can’t use steroids that will cause potent side effects, such as Superdrol, Trenbolone, Halotestin, or Anadrol;
  • Oral AAS aren’t recommended ― do not plan for Anavar, Winstrol, or Dbol cycles, as they can significantly affect your liver function;
  • Never exceed the recommended dosage, start at the lower side and increase it to moderate, but do not go for maximum;
  • Always get your blood work done and monitor your health status closely.

The safest cycle would be with Sustanon (a testosterone blend) or any test esters (Enanthate, Propionate, or Cypionate). However, you can use Primobolan or Deca Durabolin in low to moderate doses as well.

Test and Deca Cycle

Testosterone Cypionate 250mg/ml - Apoxar
Long-lasting anabolic steroid for significant muscle growth and improvements in strength and endurance. Good choice for Testosterone Replacement Therapy (TRT) Usage: Inject 500-750 mg once a week. For TRT - 250 mg once a week. Cycle
$85.00
5
Deca Durabolin - Nandrolone Decanoate 300mg/ml - Apoxar
Deca 300 mg is an injectable anabolic steroid with Nandrolone Decanoate as its active agent. Best for bulking off-season. Usage: Inject 300-800 mg once a week Cycle Duration: 8-12 weeks for optimal
$95.00
5

You can change Testosterone Cypionate for Test Enanthate or Propionate, adjusting the injection frequency accordingly. Deca Durabolin can be a great choice for increasing muscle mass and providing additional joint support.

Week

Test Cyp, mg/week

Deca, mg/week

Arimidex, mg/EOD

HCG, IU/week

Nolvadex, mg/day

1

500-600

300-400

2-6

500-600

300-400

1

7-8

2000

Off-cycle gap

9-10

40

11-12

20

It’s recommended to use HCG to boost natural testosterone production while you’re waiting for esters to clear out of your system. Your body can become more sensitive to changes in testosterone levels with age, and you can experience withdrawal symptoms after the end of the cycle.

Also, you can add Primobolan to your cycle (injectable). The recommended dosage is 250-400 mg/week. You can split the dosage into separate injections.

Test and EQ Cycle

Equipoise - Boldenone 300mg/ml - Apoxar
Boldenone 300 is an extremely effective steroid used for quality muscle gain and strength performance improvements with little to no possible side effects. Usage: Inject 300-800 mg once a week Cycle Duration: 8-10 weeks for optimal
$95.00
5
Testosterone Enanthate 250mg/ml - Apoxar
Testosterone Enanthate is used as the main compound for most steroid cycles. It's a great option for Testosterone Replacement Therapy Usage: Inject 500-1000 mg once a week. For TRT purposes - 250 mg once a week. Cycle Duration: 8-12 weeks for
$85.00
5

Equipoise, or Boldenone, is considered a compound with more pronounced side effects. However, the Test and EQ cycle is pretty popular among men over 40:

Week

Test E, mg/week

EQ, mg/week

Arimidex, mg/EOD

HCG, IU/week

Nolvadex, mg/day

1

400-500

250-500

2-16

400-500

250-500

1

17-18

2000

Off-cycle gap

19-20

40

21-22

20

Now, it’s important to note that you can’t use this cycle if you have severe cardiovascular problems, including hypertension or high LDL levels. It’s a general recommendation to use shorter cycles after 40, but with EQ, it just doesn’t make sense to go for a 10-12 week cycle.

However, if you notice symptoms such as elevated blood pressure, chest pain, or an irregular heartbeat, you should cut the cycle short and prioritize your health.

Conclusion

Going on a steroid cycle in your 40s is a better idea than starting to use steroids in your teen years or early twenties, when you peak (hormones-wise). The benefits outweigh the risks ― at least if you’re smart about it and don’t push your body too hard.