Clomid

Clomiphene Citrate

• Classification: Selective Estrogen Receptor Modulator
• Structure Non-Steroidal
• Estrogenic Activity None
• Progestational Activity None
• Water Retention: None
• Aromatization: None
• Hepatotoxicity Low
• Active Half-life: 5-7 days
• Recommended Dosage: 50-150 mg/day

Clomid General Info

Clomid is an anti-estrogen drug that is used to treat infertility. Clomid was created in 1970, and since then, it has been widely used in clinical medicine, bodybuilding, and other sports.

Clomid Classification

Clomid with its active ingredient Clomiphene Citrate is a Selective Estrogen Receptor Modulator (SERM) with agonist and antagonist properties on estrogen receptors (ER) in different tissues. Clomid is a partial anti-estrogen, and sometimes it is used for this purpose. We do not recommend Clomid for this purpose and strongly advise using more advanced and potent compounds such as aromatase inhibitors (Arimidex, Aromasin) to prevent estrogen levels spikes. Besides being a partial anti-estrogen, Clomid influences the HPTA axis and enhances the release of FSH and LH hormones, which are crucial during Post Cycle Therapie.

Clomid and the Hypothalamic-Pituitary Gland-Testes Axis (HTPA) 

Clomid stimulates Hypotolamus

Hypothalamus stimulates Pituitary Gland to release Gonadotrophic Hormones FSH and LH.

FSH stimulates the testes to produce more Testosterone

LH stimulates the testes to secrete more Testosterone

Result

The increase of endogenous Testosterone production

Clomid in Bodybuilding

All steroids taken in doses sufficient to promote muscle gains will suppress endogenous testosterone production. Some suppress it stronger, and others have a milder effect. A Post Cycle therapy after each AAS cycle is crucial and more important than the cycle itself. Clomid is the first-ever used recovery drug for Post Cycle Therapy. Clomid is a very potent and reliable compound for PCT. That is why it has been a prevalent choice for post-cycle therapies for more than five decades.

Clomid Clinical Trials

Columbia University (USA)

• Study Type: Clinical Trial
• Actual Enrollment:36 male with hypogonadism
• Sexes Eligible for Trial: Men
• Ages Eligible for Study:39-45 yo
• Baseline Testosterone Level: average of 247 ng/dL (normal range 264-916 ng/dL)
• Intervention Model: Parallel Assignment
• Primary Purpose: Raising Endogenous Testosterone Production
• Experimental Group
• Patients received 25 mg/day of Clomid a day for 12 weeks.
• Results after four weeks of Clomid Administration
• Testosterone levels rose to 610 ng/dL (average for the entire group)
• 146% increase compared to baseline levels (before treatment)

Clomid Main Benefits

• Stimulates endogenous testosterone production
• The only effective Post Cycle Therapy after Nandrolone or Trenbolone
• Partial anti-estrogen
• Improves cholesterol profile
• Decreases LDL (bad) cholesterol
• Increases HDL (good) cholesterol

Clomid Administartion

Recommended dosage 50- 150 mg/day

Cycle Lenght 4-6weeks

PCT Protocol Example

Cycle Description

Apo Test E and Nandrolone Cycle

Beginner/Intermediate Level

Primary Goals: 

• Bulking
• Very Significant Muscle Mass Gains
• Substantial strength increase

Cycle Lenght:8 weeks

Effectiveness Level: High

Week 1-8 

• Test E 400 mg/week
• Nandrolone 300 mg/week

Proper and Effective Post Cycle Therapy (PCT) protocol

• 1 Week
• HCG 1000IUs ones in 3 days 
• 2 Week
• HCG 1000IUs ones in 3 days 
• Clomid 100 mg/day 
• 3 Week
• Clomid 100 mg/day 
• 4 Week
• Clomid 50 mg/day
• 5 Week
• Clomid 50 mg/day

Clomid Possible Side Effects

Clomid at recommended dosages is considered a safe and well-tolerated compound. Less than 5% of users reported such side effects as nausea, headaches, depression, and irritability.