METFORMIN

Metformin is a tablet drug used for treating type 2 diabetes mellitus and is often used for weight loss. It is used for reducing weight due to its ability to accelerate the oxidation of fatty acids and inhibit fats synthesis. However, it affects several receptors in different tissues at once, expressed in various cellular metabolism changes.

Metformin lowers insulin level, which is necessary when losing weight because this hormone promotes the deposition of consumed nutrients into fat, especially if the main problem area is the belly. Blood glucose rises immediately after eating, causing the pancreas to release insulin immediately, which forces the tissues to consume glucose. This glucose is then stored in fats, which is why you need to eat fewer foods that cause high blood sugar levels to lose weight. One of the main advantages of Metformin is also considered its ability to suppress hunger. While taking the drug, it is essential to exercise without restrictions, thereby only increasing the cycle's effectiveness.

It is a white or colorless crystalline powder, highly soluble in water, lowers the glucose concentration in the blood and increases its tolerance. The principle of its action is to reduce the absorption of glucose, its production in the liver, thereby increasing the sensitivity of peripheral tissues to insulin, which increases the metabolism of glucose and its absorption by the body. It normalizes the lipid profile of blood plasma, reduces the content of triglycerides, cholesterol, and does not change the lipoprotein`s levels in other densities. It is famous in sport and bodybuilding for its ability to stabilize or reduce body weight.

Metformin Benefits:

• Helps to reduce body weight
• Decreases glucose concentration (during or after meals)
• Increases glucose tolerance
• Does not alter insulin secretion
• Normalizes blood plasma lipid profile
• Improves muscle glucose uptake
• Suppresses the feeling of hunger

Indications for use for weight loss:

• Follow a weight loss diet.
• Eliminate fast carbs.
• Take immediately before meals or with meals.
• Perform systematic aerobic training for better cycle efficiency.
• Take no more than 3-4 weeks.

Administration & Dosage

Metformin is taken orally, during or after a meal with water. The dosage is prescribed individually, but not more than three g/day in several doses. Most often, 500-850 mg is prescribed, 2-3 times a day. The cycle should last no more than three weeks.

The drug should be taken no more than 18-22 days, after which a break is required for 1-2 months. The supposed duration of the gap is not observed. In that case, this can lead to adaptation of the body, as Metformin cannot fully demonstrate the properties of a fat burner.

While using the substance, constantly monitor kidney function, blood glucose levels. Do not take with other sugar-lowering agents or medications. Do not use it before surgical operations and within two days after they are performed, and within two days before and after conducting diagnostic studies.

Side Effects

When used correctly, Metformin has few side effects. However, in isolated cases, there may be:

• From the digestive tract: diarrhea, nausea, vomiting
• Metabolic: hypoglycemia, weakness, drowsiness, hypotension, abdominal pain
• From the skin: rash, dermatitis
• From the part of the cardiovascular system: megaloblastic anemia

If side effects occur, then usually at the beginning of the cycle and after that quickly disappear. If the symptoms of side effects have not vanished after reducing the dosage, stop taking the drug, and immediately consult a doctor.

In case of an overdose of the substance, nausea, vomiting, diarrhea, abdominal pain, tachycardia, and drowsiness are possible. You need to be careful if lactic acidosis occurs, then you need to consult a doctor immediately .