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CLOMID (FARAN S.A.)
Clomid (synonyms - clomiphene citrate, clomiphene) – is a synthetic drug with non-steroidal structure from the threephenylethylen group of antiestrogen action. It is classified as a selective estrogen receptor modulator with dual properties: agonistic and antagonistic.
It can be explained by the fact that in some cases Clomid blocks the action of estrogen, directly affecting the receptors, and in others - activates receptors i.e. acts in body tissues like real estrogen.
If the body contains low concentrations of estrogen, then Clomid exerts moderate estrogenic effect, if increased - the anti-estrogen effect. This drug has no androgenic or progestational activity.
The drug is extremely popular in bodybuilding, powerlifting and weightlifting. In male athletes, Clomid acts as an antiestrogen due to its ability to block the influence of estrogen on the hypothalamus, that in its turn triggers a chain of reactions:
- stimulates the production of gonadotropin-releasing hormone (GnRH);
- increases the production of luteinizing hormone by the pituitary gland;
- raises levels of hormones that stimulate the testicles;
- increases the production of testosterone by the testes.
Due to the fact that Clomid influences directly the pituitary gland, it stimulates the growth of natural testosterone production. For this reason Clomid is essential for bodybuilders who take anabolic steroids. It is especially useful at the end of the course, because after discontinuation of steroids intake athletes notice decrease in endogenous testosterone production and reduction of its concentration in the body.
If you don’t restore normal testosterone levels, it will cause negative consequences, in particular, the significant losses of gained muscle mass and power rates. The absence or insufficient levels of androgens (such as testosterone) make cortisol a dominant catabolic hormone.
It directly affects protein synthesis in muscle tissue and stimulates the catabolic metabolism. Among bodybuilders, this process is called post-steroid frustrating because it can destroy almost all the muscles created. Administration of Clomid prevents this process.
Furthermore, at the end of the cycle practically all athletes face another problem of excess estrogen. The combination of ‘increased concentration of estrogen plus testosterone decrease’ significantly increases the risk of gynecomastia in bodybuilders. Administration of Clomid allows simultaneously solve the problems with excess estrogen and the risk of gynecomastia.
Basically Clomid is very effective in bodybuilding, because its ability to lower the activity of estrogen in the body prevents:
- the development of gynecomastia;
- deposition of fat and the formation of fat folds;
- accumulation of fluid in the body.
According to its characteristics Clomid is similar to Nolvadex (Tamoxifen), in fact, both drugs are interchangeable. What is preferable to take depends only on the athlete’s choice based on the comparative analysis: contraindications, side effects and price.
Clomid is usually taken with Proviron, as this combination is considered to be the most effective to reduce symptoms and improve aromatase ratio of androgens to estrogens.
Dosage and administration peculiarities
In order to preserve the results and stimulate the production of natural testosterone Clomid should be taken at a dose of 50-100 mg per day. This amount allows in two - three weeks normalize the usual level of testosterone in the body. It is not recommended to use Clomid more than 4-6 weeks.
Since Clomid cannot significantly raise the level of testosterone (the drug is characterized by a gradual rise), it is recommended to take it at the end of the cycle and during the recovery period, and for a rapid rise of the androgen hormone and its enhanced production by the body take it in combination with anabolic steroids HCG (gonadotropin).
HCG should not be taken more than for three weeks, since excessively high levels of testosterone and estrogen can cause the opposite effect. Clomid should also be used after the end of HCG cycle.
Some experts recommend using a drug at slightly different dosage and scheme for the right way out of a long course of strong steroids. In the first days of the recovery period Clomid is taken at increased dose - 150-300 mg daily, and then about two weeks at a dose of 100 mg, and continue taking until the end of the course at a dosage of 50 mg per day.
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